When hearing about hepatitis A, many people think about contaminated food and water. However, in the United States, hepatitis A is more commonly spread from person to person. Since March 2017, CDC’s Division of Viral Hepatitis (DVH) has been assisting multiple state and local health departments with hepatitis A outbreaks, spread through person-to-person contact.

The hepatitis A vaccine is the best way to prevent hepatitis A virus (HAV) infection 

• The following groups are at highest risk for acquiring HAV infection or developing serious complications from HAV infection in these outbreaks and should be offered the hepatitis A vaccine in order to prevent or control an outbreak:
  • People who use drugs (injection or non-injection)
  • People experiencing unstable housing or homelessness 
  • Men who have sex with men (MSM)
  • People who are currently or were recently incarcerated 
  • People with chronic liver disease, including cirrhosis, hepatitis B, or hepatitis C
• One dose of single-antigen hepatitis A vaccine has been shown to control outbreaks of hepatitis A.^1,2
• Pre-vaccination serologic testing is not required to administer hepatitis A vaccine. Vaccinations should not be postponed if vaccination history cannot be obtained or records are unavailable.

CDC has provided outbreak-specific considerations for hepatitis A vaccine administration and has updated its overall recommendations on the prevention of hepatitis A virus infection in the United States.